From genotype to phenotype
One fundamental aspect of conservation and evolution research is the implicit connection between genetic variation, phenotypic characteristics, and their influence on Darwinian fitness. Genetic diversity underpins many aspects of the adaptive potential of a population, and many of the fundamental concepts of the field rely on the assumed connection between genetic and phenotypic characteristics. But this connection is neither straightforward, nor always predictable.
The utility of a reference genome
In the 18 years since the completion of the Human Genome Project, the practicality of assembling full genomes for a wide range of taxa beyond ourselves has only improved. While model taxa systems have achieved genomes before many others, it is now possible for whole genomes to be assembled for a range of non-model organisms as well. But how do we assemble the genome of a species for the very first time (often de novo – literally “from the new”)? What can we do with this genome? Why is it so useful? Let’s delve into the process and outcomes of genome assembly a little more.
Predicting the future for biodiversity
Conservation biology is frequently referred to as a “crisis discipline“, a status which doesn’t appear to be changing any time soon. Like any response to a crisis, biologists of all walks of life operate under a prioritisation scheme – how can our finite resources be best utilised to save as much biodiversity as possible? This approach requires some knowledge of both current vulnerability and future threat – we need to focus our efforts on those populations and species which are most at-risk of extinction in the near (often immediate) future.
Of alleles and selection
If you’ve read this blog more than once before, you’re probably sick of hearing about how genetic variation underlies adaptation. It’s probably the most central theme of this blog, and similarly one of the biggest components of contemporary biology. We’ve talked about different types of selection; different types of genes; different ways genes and selection can interact. And believe it or not, there’s still heaps to talk about! Continue reading
The nature of phylogeography
Studying the interaction of environmental changes and species evolution is a critical component for predicting how species might – or might not – respond to new environmental stressors induced by climate change. We can study this at a variety of different levels and using many different data types, ranging from ‘traditional’ ecological studies which correlate phenotypic changes and environment to more narrower studies of ecological genetics and how allelic frequencies change in association with environmental gradients.